Mesterolone is the active substance in the brand name Proviron. Many people know it as Proviron due to its popularity, but I need to warn you that there are numerous other trade names for Mesterolone too. This is an orally active androgen and a derivative of dihydrotestosterone (DHT).
While this is an oral anabolic and androgenic steroid, the anabolic activity is so low that we could consider it inexistent. Mainly because of this, Mesterolone (Proviron) is among the most misunderstood and underestimated steroids on the market. It’s also the reason why this steroid is not as popular as others.
In short, this steroid is working as a DHT in the body – a powerful sex hormone and an androgen. DHT is playing a major role in the human body, especially when talking about males. And Proviron – Mesterolone is the purest DHT out there.
Proviron in Medicine
Like most other steroids out there, Mesterolone was created by scientists for treating various health conditions. Doctors can prescribe it for a variety of health conditions. For example, studies indicate that Proviron is helpful in treating anxiety, depression, and low libido.
After all, this steroid’s main purpose was to treat male infertility. That’s why doctors mostly prescribe it to men with low libido. But it also can be a precursor to full Testosterone Replacement Therapy (TRT).
Mesterolone – Proviron in Bodybuilding
Despite the fact that Mesterolone is not highly anabolic (actually, it has barely any anabolic strength), bodybuilders found a way to utilize it for their needs. For example, Proviron has a high binding affinity to aromatase enzymes and since it’s a DHT derivative, it won’t aromatize. In fact, it actually has anti-estrogenic properties because of the fact that it binds to aromatase enzymes.
That’s why in the past bodybuilders were using it as an alternative to aromatase inhibitors to lower estrogenic activity. Because of this, they also used Proviron as a PCT medication. Nonetheless, that’s still a mistake considering that Mesterolone is still a steroid and like any other – it has some ability to suppress the natural production of testosterone by suppressing your HPTA. While the suppression rate is far not as bad as with other steroids – it is still there. That’s why, if you want to recover from a steroid cycle, you can only use it during the cycle and maximum as a bridge between the cycle and PCT.
- Anyway, you should be aware that Proviron is far not as effective as actual aromatase inhibitors (AIs) when it comes to lowering estrogen. So, if you use it for this purpose, make sure that its abilities are enough. But it’s still best to have actual aromatase inhibitors handy, just in case.
People use Proviron (Mesterolone) during the cycle of aromatizing steroids to yield a harder look with more vascularity. But they also stack it with dry steroids to yield as hard and dry body appearance as possible. It can help you have an aesthetic look that is really hard and dry, assuming that you already have a lean body with low body fat amount.
But in both cycles, Proviron is going to help you thanks to its ability to bind to SHBG. That’s a protein that makes other steroids less effective. Mesterolone reduces that protein by binding to it and makes other steroids more efficient.
- So, Proviron enhances the efficacy of other steroids and additionally, it enhances your mood and libido! Perfect to stack with other steroids.
Stacking Proviron vs Using It Alone
Using Proviron alone is worthless. It has no anabolic properties and it doesn’t burn fat either. It can make your muscles appear harder, enhance mood and libido while boosting other steroids’ efficiency (due to lowering SHBG), and has some aromatizing properties but all only when you stack Mesterolone with other steroids. Proviron shines when you know how to use it stacking with other steroids. But it’s not effective when you use it alone for physique and performance enhancement purposes.
For example, using testosterone, it aromatizes in the body which can make you look bloated with puffy muscles. Moreover, it’s the free testosterone that makes you strong and massive, and using testosterone, a good part of it doesn’t convert into free testosterone because of SHBG.
When you add Proviron, it won’t only reduce aromatization, but make testosterone work way better too. You could stack Proviron with virtually any given steroid. Even with orals. Despite being oral itself. That’s because this steroid is not C17AA, therefore, it’s way less (if any) liver toxic.
Here’s a very basic Proviron cycle that offers mind blowing results for beginners:
- Week 1-10 Testosterone Enanthate 150-200 mg Monday and 150-200 mg Thursday.
- Week 1-10 Proviron 25 mg in the morning and 25 mg in the evening.
Mesterolone – Proviron Side Effects
Remember that Mesterolone (Proviron), although often seen as an ancillary to other steroids, is actually a steroid itself. Therefore, it’s pretty obvious that it offers the common side effects of anabolic steroids. Being a pure DHT derivative, we can learn a few things:
- It won’t offer estrogenic side effects
- Androgenic side effects can and will occur, especially if you’re prone to it
- Women are very likely to experience virilization (masculinization) issues
- Men will inhibit their HPTA and natural testosterone production
- Cholesterol and/or cardiovascular issues can still occur
- Although orally active, as said earlier, is not C17AA, thus, not hepatotoxic.
Being a milder steroid doesn’t mean that all these side effects can’t occur. They can, but since it’s milder, they are likely to be milder too, and less likely to occur in the first place.
Proviron Dosage and Half-Life
There is no injectable version of Proviron (Mesterolone) – it only comes as pills/tablets. The most common strength version of Proviron is 25 mg per tablet. Moreover, Mesterolone half-life is about 12 hours.
Therefore, in order to maintain as stable levels of this steroid in blood as possible, you need to split the daily dosage into two even halves such as every 8-12 hours.
The most common dosage of Proviron is 25-100 mg a day. Some professionals use up to 150 mg/day. While I’ve heard of people using doses as much as 200-250 mg/day – there’s just no point in doing that. Doses over 150 mg/day are offering no further benefits but the side effects risk greatly increase.
Very common dosage is 50-75-100 mg/day = 2-3-4 pills split throughout the day. Because it’s not C17AA, you could use it for as long as you want. But I only recommend using it for as long as your steroid cycle lasts (remember that there’s no point in using Proviron alone).
I wouldn’t recommend Proviron for females at all because of its strong DHT properties. But those who use it, run a maximum of 25 mg a day for a maximum of 5 weeks. It’s important to understand that even this seemingly low dosage and the short cycle is already very possible to cause virilization issues in a woman.
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