Sibutramine is a product that used to be legal in the USA up until 2010 when the FDA prohibited the sales of this drug. Nonetheless, a lot of people still use this compound with a high success rate for weight loss purposes.
The most popular brand was Meridia. Developed and marketed by Knoll Pharmaceuticals originally, then by Abbott Laboratories until it got banned. Nowadays you can find Sibutramine pills in numerous brand names including Sibuzone.
What is Sibutramine?
Sibutramine (Meridia, Sibuzone including others) is a diet medication that was categorized as an appetite suppressant. Users of Sibutramine report they had great success when it comes to aiding body fat loss and general weight loss. That’s because it does a great job of lowering the users’ appetite. Athletes were experiencing lower appetite and when they combined it with proper diet and exercise, they had great success.
That’s because, in order to burn fat off and lose weight, users need to consume fewer calories than their body burns. Eating less, thanks to Sibutramine (reduced hunger feeling and cravings), they were consuming considerably fewer calories than they burn.
However, I should warn you that burning way too many calories is not a good idea. While Sibutramine is an awesome option to suppress appetite, make sure that you’re eating enough calories in a cutting diet in order to ensure you don’t lose muscles.
It’s a great option for those who are searching for weight loss cycles (and don’t really care about muscle maintenance). And while it’s a great option for cutting cycles too, make sure you’re not drastically undereating.
How Does Sibutramine Work?
Most other appetite suppressant drugs that we know are working as releasing agents. However, Sibutramine is working in different ways as it’s not a releasing agent.
Other suppressants are getting inside the cells and they boost the release of neurotransmitters like for example serotonin. Sibutramine, however, is an uptake inhibitor. This means that this drug is working outside the cells by stopping serotonin from being reabsorbed by the Serotonin Norepinephrine Reuptake receptors. This is why this compound is an SNRI (Serotonin and Norepinephrine Reuptake Inhibitor).
As a result, the overall appetite control effect is lasting longer and is highly efficient. But in order to better understand how Sibutramine works, you need to understand what Serotonin is.
This is a neurotransmitter in the body. It has a very close connection to your mood, sleep, and appetite as serotonin is what actually regulates them. Very often, anti-depressant drugs contain serotonin inhibiting compounds. That’s why antidepressants have the ability to drastically decrease or increase appetite. Moreover, such types of substances are often used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD). But there are other health conditions where they can be helpful.
Meridia (Sibutramine), however, was mostly given to patients to help them lose weight or maintain their weight loss. Obviously, before it got banned. This product was helpful in combination with a low calorie diet and exercise plan.
Sibutramine Legality
Sibutramine pills are currently not allowed in the United States because it is a schedule IV drug. This means that the drug or other substances are having the potential for abuse relative to drugs in schedule III. It means that abusing this compound is likely to lead to physical or psychological dependence.
According to studies, some people were developing side effects related to heart attack and stroke. That’s why Sibutramine is currently not allowed in the USA.
However, this was also the first drug to be approved for obesity treatment in a time span of 30 years! Clinical studies suggest that it was actually highly effective for people suffering from obesity or those who want to lose weight. For example, there’s a clinical study that involved 5,000 patients of both genders and various different ages. According to that study, on average, patients managed to lose 10% of their original body weight!
Sibutramine in Bodybuilding
Bodybuilders and athletes report great results in terms of curbing their appetite. That’s why, many people all around the world experience a noticeable decrease in appetite when they use Sibutramine (Meridia, Sibuzone including others).
They claim that the best way to use it is in the morning as it helps control their appetite and it’s helpful at avoiding cheat meals. It also helps with less craving for junk food.
Sibutramine is nowadays not as popular as other weight loss compounds, especially because of its ban status. A lot of bodybuilders are running stimulants for their weight loss goals such as Clenbuterol. While Clenbuterol, for example, does have slight appetite suppression effects, this is not an appetite suppressant. It works in completely different ways.
Sibutramine Dosage and Half-Life
Sibutramine comes in oral form only, that’s why you can find it as Sibutramine pills. This compound is metabolized by cytochrome P450 isozyme CYP3A4. This is resulting in 2 active amines. These are the primary and the secondary amines. Or you simply call them active metabolites 1 and 2.
In the end, it leads to a fairly long half life of about 14 to 16 hours but the peak plasma concentrations are reached after about 3-4 hours.
Usually, bodybuilders and most other users use it once a day, in the morning as soon as waking up. They may use it with or without food.
The common starting dosage is 10 mg/day. May increase to 15 mg/day when you have an experience of at least 4 weeks with it and you think that you don’t experience the desired results.
Because of different sizes and weights, some bigger bodybuilders may increase the dosage slightly more.
The total length of Sibutramine cycle use is around 8 weeks or more. However, it’s important to understand that you’re likely to recover the weight back if you won’t find ways of controlling your appetite naturally.
Sibutramine Side Effects
As I already mentioned earlier in this post – Sibutramine is a compound that has a dependence liability. This means that it could be harder for you to get off it. That’s why it is important to start with low doses and shorter cycles to see how it goes.
Moreover, I also mentioned that the USA FDA banned Sibutramine because of the heart related risks and stroke. That’s why, people suffering from heart related issues, cardiovascular problems, increased heart rate, or high blood pressure are more likely to experience negative side effects and get their condition worse.
- Some of the most common side effects that bodybuilders report are: insomnia and jitters.
*Again, start with lower doses and take it the first thing in the morning, which can help with insomnia.
- Other possible side effects are: dry mouth, dizziness, headaches, nausea, stomach issues as well as joint/muscle pain in some instances.
Where Can I Buy Sibutramine Pills?
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You can buy Sibutramine pills for sale at Supps-For-Life.to that would do a great job in curbing your appetite. However, as you can see, there are some side effects possible too (as with most other Performance Enhancing Drugs).
So, I strongly recommend you to be careful with it and pay attention to how you’re using it. Pay attention to where you buy it from too. Since you can only get it on the black market, there’s a high chance of getting bunk.
If you’re sure you want Sibutramine to control your appetite, Supps-For-Life.to is your best bet when it comes to offering quality products for the cheapest prices!
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