Aromatase Inhibitors

Aromatase Inhibitors (AIs) are medications that are lowering estrogen levels in your body by stopping aromatization. They are doing so by binding to the aromatase enzymes (some enzymes in fat tissue) and blocking their conversion from testosterone into estrogen.

Estrogen is a very important hormone. Although there’s a common myth that this is a female hormone, it’s very important for males too. Nonetheless, in case you get lots of estrogen levels, it causes various “high estrogen related” side effects. For example, estrogen is promoting the growth of breast cells leading to gynecomastia (male breast enlargement).

Aromatase Inhibitors are extremely helpful for women suffering from hormonally positive breast cancer. That’s a form of cancer that is forming and growing because of estrogen. So, when you use AIs and they lower estrogen, it’s obvious that they are hindering the development and progression of such types of breast cancer. That’s why Aromatase Inhibitors (AIs) are so immensely helpful and effective in dealing with breast cancer in women.

Aromatase Inhibitors in Bodybuilding

So, it’s clear why women use Aromatase Inhibitors, but why would men use them? They are especially popular among bodybuilders who use anabolic and androgenic steroids (AAS). Using steroids, men increase muscle growth and stress and at the same time, they are burning fat too. Yet, steroids are very similar to testosterone (structurally) and that’s why most of them are converting into estrogen. Not all steroids convert into estrogen though.

But if you use steroids that do convert into estrogen (such as testosterone among many others), males can have a high amount of estrogen in the body. This can lead to various estrogen symptoms such as developing gynecomastia (bitch tits) including others. It occurs because they have higher levels of testosterone which allow for more testosterone to convert into estrogen. Thus, using aromatizing steroids leads to higher estrogen levels. That’s when Aromatase Inhibitors (AIs) are getting so helpful.

By using AIs, men can continue using steroids while keeping estrogen levels low (in the normal range). Therefore, they can prevent or deal with gynecomastia and all other high estrogenic symptoms. You may use them as preventative measures, as long as you have enough experience, but you may also use them as treatment plans for dealing with gynecomastia and other estrogenic symptoms.

The reason that you should have experience first, before using them as preventative measures, is that using Aromatase Inhibitors may lower too much estrogen. That’s an important hormone for both men and women. If you crush too much estrogen with AIs, it is very likely to suffer from low estrogen symptoms.

When Should I Use AIs?

Generally, I recommend using Aromatase Inhibitors (AIs) only when you’re using steroids that do aromatize into estrogen. As said, not all steroids aromatize and if you use a very low dosage of testosterone for example with non-aromatizing steroids, you may not need any AIs at all. But if you stack aromatizing steroids, especially in higher dosages, the need for Aromatase Inhibitors is imperative.

It’s also pretty obvious that the higher the dosage of aromatizing steroids you use during the cycle, the more likely you are to require AIs and in higher doses too.

You may start using AIs immediately after starting the cycle, but make sure you do not overdo it and do not suppress too much estrogen. That’s why, most people start to use an Aromatase Inhibitor at the onset of the first high estrogen symptom.

Types of Aromatase Inhibitors

There are various different Aromatase Inhibitors (AIs) and when talking about AIs in bodybuilding, there are generally three main ones. Considering that they are all lowering estrogen, they are offering pretty much the same results and the same side effects with little difference. Check them below:

• Arimidex (Anastrozole). This is among the most popular aromatase inhibitors. Anastrozole does a great job of lowering estrogen levels. The typical dosage is about 0.5 mg up to 1 mg from every other day up to once a week or even less infrequent administration.

• Femara (Letrozole). Letrozole is working in the same way as Anastrozole, but it is way more powerful. In fact, Femara is the most powerful out of all other AIs out there. Femara will crush estrogen levels very fast and very efficiently. That’s why bodybuilders generally use Letrozole only if they are developing gynecomastia and need to deal with it. Or when other AIs are ineffective. Dosage ranges between 0.25 mg EOD up to about 1 mg ED.

• Aromasin (Exemestane). Aromasin also works by binding to aromatase enzymes but unlike the other two AIs, Exemestane binds to those enzymes permanently. This means that there’s no chance that those enzymes would rebound, as with the other two AIs. This removes the possibility of estrogen rebound when stopping the use of AI. That’s why Exemestane is considered superior. A typical dosage for bodybuilders is about 12.5 mg EOD or even less frequently.

Conclusion

In the end, Aromatase Inhibitors are indispensable tools for bodybuilders who are using anabolic steroids. Although AIs come with their own risks and side effects, not using any Aromatase Inhibitors when you actually need them comes with even higher risks.

It’s very important to run AIs and not allow estrogen spikes too much. It can lead to various high estrogen symptoms. Some of the most common high estrogenic issues among bodybuilders are:

• Gynecomastia (male breast enlargement AKA bitch tits)
• Water retention
• Bloating
• Erectile dysfunction
• Affecting your mood
• Low sex drive
• And others too

But if you use too much Aromatase Inhibitors (AIs) dosage or use them when you don’t need them – it could lead to crushed estrogen levels. Some symptoms include:

• Low mood
• Erectile dysfunction
• Muscle and/or strength loss
• Tiredness
• Joint pains and dryness
• And others too

In the end, make sure to have Aromatase Inhibitors (AIs) handy if you want to use anabolic steroids.

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